Identification of controlled substances
The first step towards meeting compound compliance legal requirements is the identification of controlled substances such as narcotics, psychotropic drugs, and chemical weapons. Compliance Checker is a combination of a software system and a regularly updated content package providing a flexible tool to screen chemical structures efficiently against the controlling legislation. It is available both as SaaS and on-premise distributions.
Dealing with controlled substances at a pharmaceutical company or in any other life science R&D organization, one must implement rigorous controls to meet the requirements set by the regulatory bodies covering both production, possession, import/export, transportation and disposal of such substances. If by any chance such law, regulation, or ordinance is violated, it may cause the loss of reputation, sales, and can also result in financial and criminal penalties.
Compliance Checker is a nexus between software and content package providing a flexible tool fitting in all compound compliance workflows. It screens chemical structures efficiently against the controlling legislation. Compliance Checker channels knowledge into your system about controlled substances.
Compliance Checker relies on a comprehensive knowledge base made up of relevant legislation of 18 countries and 5 international regulations. The regular updates are guaranteed at no additional cost. Resources are continuously monitored and new regulations are immediately extracted and are automatically merged to the knowledge base
Regulations are transformed into chemical query structures that are matched against the substances to be checked. The search runs using ChemAxon’s JChem Engines, which enables the finding of isomeric forms, salts and makes sure that the exceptions are not found. The integrated Markush technology makes it possible to cover generic regulations. Upon request, we can extend the geographical coverage, include further legislations, or add internal corporate regulations into the knowledge base.
Compliance Checker’s Software as a Service model has two major categories: Standard and Lite subscriptions. The Standard version is empowered with Compliance Checker’s full feature set including every platform (GUI, API, Pipeline Pilot and KNIME nodes), including the full Administration area. While on-premise installers are available, the SaaS model is more beneficial as it provides an instantly accessible, pre-deployed distribution in the cloud, which is automatically updated and maintained by ChemAxon.
The competitively priced Lite subscriptions are created for those small and medium-sized companies which need a state-of-the-art compliance solution and are ready to make compromises in terms of the number of users, molecules to be checked, and speed. In ChemicalizePro only a very basic API is offered.
Seamless integration is a key feature of Compliance Checker. The Integration API via RESTful web services and Chemicalize Pro offer several options on how to add compliance information to your proprietary systems such as compound registration system, inventories, and ELN. By connecting the system to your corporate authentication and assigning the corresponding roles to your user groups, you can easily control the accessibility and support the user workflows in an optimal way.
When integrating Compliance Checker into your environment, performance can be an important factor. Thanks to its microservices architecture, it can easily fulfill any realistic requirements due to the almost linear scale up with CPU or the number of computation service instances. The Premium Subscription of Compliance Checker is able to accomplish the compliance check of 45 million research compounds against all covered countries on a weekend.