KNOWTOX, a Franco-Hungarian collaborative project relative to toxicity
Drug-induced hepatotoxicity or liver damage/disease is a major concern during the drug development process. Toxicity knowledge exists but data is scattered in numerous sources and can not easily be accessed simultaneously. The goal of the Franco-Hungarian project KnowTox is to build a new knowledge base related to hepatotoxicity as well as predictive tools for the automated prediction of metabolites and their toxicity to extend the value of the system. Having access to a knowledge database containing detailed biological and chemical data and associated analysis applications will lead to better use of available knowledge and time and costs saving during drug development.